Page 50 - THE GLOBAL LEADER IN MEMBRANE SEPARATION INDUSTRY

PART 02 Proficient in membrane technology and
customized processes as needed

Biofermentation products Application Products

Separation and purification of fermentation broth is an important part of the production
process of biofermentation products, which will directly affect the overall cost and product quality
Enzyme preparation and
and yield. The composition of fermentation broth is very complex, generally containing mycelium, Amino acid and derivative
biological product
particulate matter, soluble impurity, residual solid bacilli solid culture medium, ash, water and
target products, etc. The traditional separation techniques mainly include adsorption,
Chemical raw materials and
precipitation/sedimentation, solvent extraction, isoelectric point, ion exchange, etc., which are Biochemicals
pharmaceutical intermediates
mainly characterized by the problems of low yields, poor control of product quality, complicated
processes, long time-consumption, high energy consumption and serious pollution. Nowadays,
membrane separation and purification technology has become the mainstream application in
Vitamins and probiotics Other products
biofermentation industry.

Application
Technical advantages
Crude separation: cell recovery, protein filtration, removal of mycelium.
Fine separation:clarification, separation, decolorization, desalination, concentration, desolvation
(including dehydration).
· Good chemical stability, high filtration efficiency, pure physical filtration process, no need to add any filter aid;
Resource utilization: acid and alkali recovery, mother liquor recovery, enzyme recovery.
Process wastewater treatment: standard discharge, deep treatment, water reuse, zero discharge · Good stability, good anti-biofouling capability, Can design production conditions suitable for high
and resource utilization. temperature, high pressure, and acid-base corrosion;
Core Technology · Ceramic membrane filtration has a long service life and slow membrane flux decay, general service
life of 5 to 8 years;

· Organic membrane filtration can realize molecular weight cutting off and desalination with superior
performance and high yield, which can reach more than 98.5%;

· Compared with centrifuge and plate frame filtration, the membrane filtration transmits lower impurity
content, higher product purity and lower burden of follow-up processes；
· Compared to outdated processes, it can significantly reduce system investment, reduce system footprint,
save engineering support, and save energy consumption；
· High degree of automation, reducing personnel investment and labor intensity, optimizing the production
environment;

· Simple operation and maintenance of membrane system, high recovery rate of one-time cleaning.

Ceramic membrane continuous filtration system Ultrafiltration decolorization of an amino acid project
of a threonine producer in Inner Mongolia in Shandong Province

Organic membrane treatment of amino acids project Ceramic membrane continuous filtration system Membrane integrated system of a pharmaceutical Organic membrane purification system of a vitamin
in Inner Mongolia of a dibasic acid producer in Ningxia company in Zhejiang Province producer in Hebei Province

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